Ollama

Ollama is the most popular tool for running large language models locally, with 52 million monthly downloads and 165K+ GitHub stars. Run any model with a single command (ollama run qwen3.5). Handles model downloading, quantization, GPU memory allocation, and serves an OpenAI-compatible API on localhost. Supports hundreds of models including Kimi-K2.5, GLM-5, DeepSeek, Qwen, Gemma, Llama, and Mistral. Features tool calling support and optimized GPU utilization.